Glutathione and associated enzymes in toxic cataractogenesis-selenite model.

نویسندگان

  • Joe Prasad Mathew
  • Priya Joseph
  • V C Thomas
  • Issac Thomas
چکیده

Glutathione, gamma-glutamyl cysteine synthetase (gamma -GCS) and glutathione reductase (GSH-R) activity were determined biochemically in the lens during various stages after subcutaneous administration of sodium selenite in multiple low dosages and single high dosages. The GSH concentration and gamma-GCS and GSH-R activity declined progressively after the selenite administration. The changes observed were discussed in relation to the possible role of selenite interaction with GSH and the enzymes.

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عنوان ژورنال:
  • Journal of environmental biology

دوره 27 4  شماره 

صفحات  -

تاریخ انتشار 2006